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产品基本信息
产品编号：F595465
产品名称：3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one
产品CAS：189028-95-3
规格含量：5g
产品价格：面议
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产品详细介绍
标准品编号:
F595465
名称:
3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one
别名:
(4S)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one; [S-(R*,R*)]-3-[5-(4-Fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone; (S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
CAS号:
189028-95-3
分子式:
C₂₀H₂₀FNO₄
外观:
白色至白色固体
熔点:
54-59ºC
分子量:
357.38
储存:
-20°C Freezer
溶解度:
Chloroform (Slightly), Methanol (Slightly)
种类:
Building Blocks; Chiral Molecules;
应用:
3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one is an intermediate of Ezetimibe (E975000, E975002), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.
参考文献
Singh, A., et. al.: J. Molecular Catal. B., 85, 99 (2013); van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)
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