2-Methyl-2-[4-[2-methyl-8-[(pyridin-3-yl)ethynyl]imidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile; BAG 956; NVP-BAG 956; α,α-Dimethyl-4-[2-methyl-8-(3-pyridinylethynyl)-1H-imidazo[4,5-c]quinolin-1-yl]benzeneacetonitrile
CAS号:
853910-02-8
分子式:
C₂₈H₂₁N₅
外观:
白色固体
熔点:
>224ºC (dec.)
分子量:
427.5
储存:
-20°C Freezer
溶解度:
DMSO (Slightly, Heated), Methanol (Slightly)
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
NVP-BAG956 acts as a rapamycin inhibitor used in the treatment of various melanomas through cell-induced apoptosis. Also used in antileukemic therapies as a dual PI3K/PDK-1 inhibitor.
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