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产品基本信息
产品编号：N605000
产品名称：NKH 477
产品CAS：138605-00-2
规格含量：10mg
产品价格：面议
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产品详细介绍
标准品编号:
N605000
名称:
NKH 477
别名:
N,N-Dimethyl-β-alanine (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl Ester Hydrochloride; N,N-Dimethyl-β-alanine [3R-(3α,4aβ,5β,6β,6aα,10α,10aβ,10bα)]-5-(Acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl Ester Hydrochloride; 1H-Naphtho[2,1-b]pyran, β-alanine deriv.; 6-(3-Dimethylaminopropionyl)forskolin Hydrochloride; Adehl; Colforsin Dapropate Hydrochloride
CAS号:
138605-00-2
分子式:
C₂₇H₄₄ClNO₈
分子量:
546.09
种类:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
NKH 477 is a water-soluble analog of Forskolin (F701800), that is a potent activator of adenylyl cyclase, which shows some selectivity for cardiac (type V) adenylyl cyclase).
参考文献
Hirasawa, A. et al.: J. Cardiovasc. Pharmacol., 22, 847 (1993); Ito, S. et al.: Brit. J. Pharmacol., 110, 1117 (1993);
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