Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
(R)-Methyl 4-((3R,5S,8S,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7-bis((trimethylsilyl)oxy)-2,3,4,5,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate is an impurity of obeticholic acid, a semi-synthetic analogue of human bile acid that activates farnesoid X receptor. Obeticholic acid also inhibit liver fibrosis development.