Standards; Isotopic Labeled Analogues; Environmental Standards, Mutagens and Metabolites;
应用:
Labelled trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNVIP(LA)adducts primarily with 2'-deoxyguanosine. A carcinogen.
危险品:
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
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