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产品基本信息
产品编号：V128620
产品名称：Vernakalant Hydrochloride
产品CAS：748810-28-8
规格含量：5mg
产品价格：面议
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产品详细介绍
标准品编号:
V128620
名称:
Vernakalant Hydrochloride
别名:
(3R)- 1-[(1R,2R)-2-[2-(3,4-Dimethoxyphenyl)ethoxy]cyclohexyl]-3-pyrrolidinol Hydrochloride; (1R,2R)-2-((3R)-Hydroxypyrrolidinyl)-1-(3,4-dimethoxyphenethoxy)cyclohexane Monohydrochloride; (1R,2R)-2-((3R)-Hydroxypyrrolidinyl)-1-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexane Monohydrochloride; (3R)-1-[(1R,2R)-2-[2-(3,4-Dimethoxyphenyl)ethoxy]cyclohexyl]-3-pyrrolidinol Monohydrochloride; RSD 1235
CAS号:
748810-28-8
参考CAS号:
free base: 794466-70-9
分子式:
C₂₀H₃₂ClNO₄
外观:
白色至淡黄色固体
熔点:
151-153ºC
分子量:
385.93
储存:
Hygroscopic, 冰箱, under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
类别:
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Vernakalant Hydrochloride is a novel, relatively atrial-selective antiarrhythmic drug that effectively and rapidly terminates atrial fibrillation (AF).
参考文献
Mao, Z.L., et. al.: J. Clin. Pharmacol., 52, 1042 (2012); Mao, Z., et. al.: J. Pharmacokinet. Pharmacodynam., 38, 541 (2011)
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