Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methylpicolinamide is an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.