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10-Hydroxy-11-methoxycamptothecin
产品基本信息
产品编号:H949833
产品名称:10-Hydroxy-11-methoxycamptothecin
产品CAS:
规格含量:2.5mg
产品价格:面议
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产品详细介绍
标准品编号: H949833
名称: 10-Hydroxy-11-methoxycamptothecin
分子式: C₂₁H₁₈N₂O₆
分子量: 394.38
种类: Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用: 10-Hydroxy-11-methoxycamptothecin can be obtained from (S)-(+)-Camptothecin (C175150) which is an antitumor alkaloid. It binds irreversible to the DNVIP(LA)topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent.
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