1,3-Bis(trimethylsilyl)-1H-imidazol-3-ium Chloride is an intermediate for the synthesis of 2’,4’’-O-Bis(trimethylsilyl)erythromycin A 9-O-(1-Ethoxy-1-methylethyl)oxime (B585424), which is an intermediate used in the synthesis of clarithromycin, a macrolide antibiotic and other antibiotics.