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产品编号：A822005
产品名称：8-Azidoadenosine-5'-diphosphate Sodium Salt
产品CAS：102185-14-8
规格含量：2.5mg
产品价格：面议
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产品详细介绍
标准品编号:
A822005
名称:
8-Azidoadenosine-5'-diphosphate Sodium Salt
CAS号:
102185-14-8
备用CAS:
Free Base: 59432-65-4
分子式:
C₁₀H₁₄N₈O₁₀P₂ • 2Na
分子量:
468.2122299
类别:
Research Tools;
应用:
8-Azidoadenosine-5'-diphosphate Sodium Salt is potentially utilized as a photo-affinity probe commonly in combination with 32P. Long wavelength UV light activates the Azido group which then creates a nitrene moiety. This reactive nitrene is then able to covalently bond with residues of target proteins.
文献
文献: Gzarnecki, J., et al., Methods in Enzymol., v. 56, 642 (1979). Cho, S.W., Yoon, H.Y., "Photoaffinity labeling of brain glutamate dehydrogenase isoproteins with an azido-ADP." J. Biol. Chem., v. 274:20, 13948-13953 (1999). Ward, D.G., Cavieres, J.D., "Photoinactivation of fluorescein isothiocyanate-modified Na,K-ATPase by 2'(3')-O-(2,4,6-trinitrophenyl)8-azidoadenosine 5'-diphosphate. Abolition of E1 and E2 partial reactions by sequential block of high and low affinity nucleotide sites." J. Biol. Chem., v. 273:23, 14277-14284 (1998). Shoemaker, M.T., Haley, B.E., "Identification of adenine binding domain peptides of the ADP regulatory site within glutamate dehydrogenase." Bioconjug. Chem., v. 7:3, 302-310 (1996). Lacapere, J.J., Garin, J., Trinnaman, B., Green, N.M., "Identifica
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