AT 9283; 1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea; N-Cyclopropyl-N'-[3-[5-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]-urea
CAS号:
896466-04-9
分子式:
C₁₉H₂₃N₇O₂
外观:
白色固体
熔点:
>164°C (dec.)
分子量:
381.43
储存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
类别:
Research Tools; Enzyme Activators and Inhibitors;
应用:
AT-9283 is a potent AuroraA/AuroraB and multi-kinase inhibitor. AT-9283 has shown to inhibit growth and survival of multiple solid tumor cell lines and is efficacious in mouse xenograft models.
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