Trifluoromethyl Cyclopropyl Ketone is a derivative of Cyclopropanecarboxaldehyde (C989650); a reagent used in the preparation of N-alkylphenylalaninamides from pyridinylphenyl- and oxobipyridinylamines as human GPR 142 agonists for potential use as anti-diabetic agents and the cytochrome P 450 inhibition.