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产品基本信息
产品编号：M425040
产品名称：MK-8745
产品CAS：885325-71-3
规格含量：50mg
产品价格：面议
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产品详细介绍
标准品编号:
M425040
名称:
MK-8745
别名:
(3-Chloro-2-fluorophenyl)[4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-1-piperazinyl]-methanone; 1-(3-Chloro-2-fluorobenzoyl)-4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-piperazine; 6-[[4-(3-Chloro-2-fluorobenzoyl)piperazin-1-yl]methyl]-N-(thiazol-2-yl)pyridin-2-amine
CAS号:
885325-71-3
分子式:
C₂₀H₁₉ClFN₅OS
外观:
白色固体
熔点:
177-179°C
分子量:
431.91
储存:
冰箱
溶解度:
DMSO (Slightly), Methanol (Slightly, Heated)
种类:
Standards; Enzyme Activators and Inhibitors;
应用:
MK-8745 is a potent and selective Aurora A kinase inhibitor that induces apoptotic cell death in a p53-dependent manner when tested in vitro in cell lines of multiple lineages.
参考文献
Nair, J.S., et al.: Cell Cycle, 11, 807 (2012); Chowdhury, A., et al.: Leukemia Lymphoma, 53, 462 (2012)
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