PHA-848125_802539-81-7_P294490_【莱耀标准品网】

产品基本信息

产品编号：P294490

产品名称：PHA-848125

产品CAS：802539-81-7

规格含量：5mg

产品价格：面议

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产品详细介绍

标准品编号:	P294490
名称:	PHVIP(LA)848125
别名:	Milciclib; N,1,4,4-tetramethyl-8-((4-(4-methylpiperazin-1-yl)phenyl)amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide
CAS号:	802539-81-7
分子式:	C₂₅H₃₂N₈O
分子量:	460.57
类别:	Research Tools;
应用:	PHVIP(LA)848125 is a cyclin dependent kinase (CDK) inhibitor. Oral PHVIP(LA)848125 showed antitumor activity via dual targeting of cyclin-dependent kinase and tropomyosin receptor kinase families in human carcinoma cell and xenografted mouse model of carcinoma.
参考文献	Brasca, M.G., et. al.: J. Med. Chem., 52, 5152 (2009); Albanese, C., e. al.: Mol. Cancer Ther., 9, 2243 (2010)

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