Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
BAN ORL 24 Dihydrochloride, is a potent and selective KOR-3 (NOP) antagonist. It inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro and antagonizes NOP agonist-induced reduction in locomotor activity in vivo.
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