6-(2,4-Difluorophenoxy)-2-[[3-hydroxy-1-(2-hydroxyethyl)propyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one; R 1503; Ro 4402257;
CAS号:
449811-01-2
分子式:
C₁₉H₂₀F₂N₄O₄
外观:
白色固体
熔点:
158-160°C
分子量:
406.38
储存:
-20°C Freezer
溶解度:
DMSO (Slightly), Methanol (Slightly)
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
A selective inhibitor of the α-isoform of p38 MAP kinase. It is used in in treatment of patient with rheumatoid arthritis. Pamapimod was tolerable but not effective as Methotrexate.
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