(2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile; (E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile; (E)-3-(p-Tolylsulfonyl)-acrylonitrile; BAY 11-7821; BAY 117821
CAS号:
19542-67-7
分子式:
C₁₀H₉NO₂S
外观：
白色固体
熔点:
129-131°C
分子量:
207.25
储存:
Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度:
Chloroform (Slightly), Methanol (Slightly)
类别:
Standards; Enzyme Activators and Inhibitors;
应用:
BAY 11-7082 is a nuclear factor-κB (NF-κB) inhibitor and a potential anti-inflammatory agent. It selectively and irreversibly inhibits NF-κB activation by blocking TNF-α-induced phosphorylation of Iκβα without affecting constitutive Iκβα phosphorylation.
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