CC 292; N-[3-[5-Fluoro-2-[[4-(2-methoxyethoxy)phenyl]amino]pyrimidin-4-ylamino]phenyl]acrylAmide; Spebrutinib; N-[3-[[5-Fluoro-2-[[4-(2-methoxyethoxy)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-2-propenamide
CAS号:
1202757-89-8
分子式:
C₂₂H₂₂FN₅O₃
分子量:
423.44
类别:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
AVL-292 is a potent and specific Bruton's tyrosine kinase (Btk) inhibitor. Studies showed that AVL-292 used in combination with Carfilzomib (C183460) impacted the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.
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